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Home » PhotoChems™ (Search By Pathway) » Nuclear Maintenance » Telomerase

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stavudine, 3′-Deoxy-2′,3′-didehydrothymidine  
stavudine, 3′-Deoxy-2′,3′-didehydrothymidine

Caged at red
Size: 100 μl
Concentration: 1 mM

A reverse transcriptase inhibitor that causes a consistent and rapid shortening of telomeres in Tetrahymera. Shown to decrease the proliferative activity of Jurkat and L1210 cell lines as well as human peripheral blood mononuclear cells at 250 μM concentration.

References

Beltz, L., et al. 1999. Anticancer Res. 19, 3205. Strahl, C., and Blackburn, E.H. 1994. Nucleic Acids Res. 22, 893. Lin, T.S., et al. 1987. Biochem. Pharmacol. 36, 2713.

Price: $27.33

Caged: YesNo

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